Lifeline® ProPlus+ Daily Defense Complex

(5 customer reviews)

$160.00All Lifeline® ProPlus+ orders ship free.

  • Restores your skin’s ability to rejuvenate itself.
  • Environmental protection while diminishing wrinkles & increasing firmness.
  • Absorbs quickly & gets to work almost immediately.
  • Uses nanotechnology to deliver a powerhouse of cytokines, potent peptides, protective antioxidants, & growth factors.
  • Non-greasy formula & non-comedogenic.
  • Each tube lasts for 5-6 weeks.

Pair with Lifeline® ProPlus+ Recovery Night Moisture Serum for best results.

$160.00All Lifeline® ProPlus+ orders ship free.

Lifeline® ProPlus is a professional line of products containing more stem cells/growth factors than regular Lifeline products. The ProPlus collection is only available through physician partners and skin care professionals.

Lifeline® ProPlus+ Before & After 1 Month
Paraben, Gluten, & Silicone Free. Not tested on animals.


Lifeline® ProPlus+ is the #1 Way to Reverse Aging Skin

Lifeline® ProPlus+ Daily Defense Complex

  • Visibly firms, tones, & defends skin every day.
  • Immediately begins restoring skin’s ability to heal & regenerate.
  • Diminishes the appearance of lines & wrinkles.
  • Visibly restores tone & texture of sagging, aging skin.
  • Absorbs quickly using nanotechnology to deliver a powerhouse of cytokines, potent peptides, growth factors, enzymes, protective antioxidants, amino acids, & more.
  • Pair with Lifeline® ProPlus+ Recovery Night Moisture Serum for best results.

Get the Lifeline® ProPlus+ Day & Night Duo for maximum anti-aging power and the best value.

How long does it take?*

  • Within 24 hours – reversal of dry skin begins.
  • Within 1-2 weekreversal of skin dullness & texture improvement.
  • Within 2-3 weeks reversal of redness – including rosacea.
  • Within 4-5 weeks – reversal of fine lines & noticeably firmer skin. Clinical studies recorded a 30% reduction of lines and wrinkles.
  • Within 5 weeks – reversal of melasma – skin pigmentation – common in women post pregnancy.
  • Within 8 weeks – visibly diminished pore size.
  • Within 12 weeks – very noticeably firmer skin. Clinical studies studies measured a 77% improvement in wrinkle length & depth.

*This timeline reflects results when using both Lifeline® ProPlus+ Day & Night products.

Morning and bedtime:

Apply 2 pumps of the daytime or nighttime serum to a clean dry face*. Neck and décolletage treatment requires an extra pump.

Less than two minutes, twice a day, is all it takes to start on an immediate path to looking younger. These highly advanced and smooth-feeling serums absorbs immediately into your skin, utilizing nanotechnology to deliver a powerhouse of Stem Cell Cytokines, Protective Antioxidants, and Potent Peptides.

*If you are using Retin-A, you apply that in a thin layer first, then the serum.
*If you are using hydroquinone, you apply that first, then the serum.

*Before & afters are based on using both Lifeline® ProPlus+ Day & Night products.

Lifeline® ProPlus+ Skin Care researchers and formulators combined the latest discoveries in the fields of stem cell biology, nanotechnology, and skin products formulation technology to create the highest quality, scientifically tested and most effective anti-aging skincare products. Lifeline® ProPlus+ Stem Cell Extract Serums are the only products in the world that contain human, non-embryonic stem cell extracts.

Only International Stem Cell Corporation (Lifeline®’s parent company) has a patented way to take human eggs and stimulate them to begin dividing, without being fertilized.

They’re called parthenogenetic stem cells (“partheno” comes from the Greek word for virgin). To produce these stem cells, an embryo is never created, so it’s never destroyed—that’s why it’s an ethical approach to creating stem cells.

While the stem cells are still pluripotent, scientists extract growth factors, cytokines, enzymes, and peptides for use in Lifeline® ProPlus+ stem cell serums. Because they’re several generations away from the source, adult stem cells (such as from skin, blood, fat or bone marrow) are far less potent than stem cells closer to the original egg-the parthenogenetic stem cells used in Lifeline® ProPlus+ products.

Non-embryonic stem cells are by far the most potent human stem cells that we can ethically use.

For more science, click here.


Lifeline® ProPlus+

Skin Concerns

Anti-Aging, Discoloration, Dryness, Dullness, Fine Lines & Wrinkles, Firmness / Elasticity, Pores, Redness, Skin Inflammation, Uneven Skin Tone

Focus Area

Face & Neck


Antioxidant, Non-Comedogenic

Key Ingredients

Stem Cell Peptides

Skin Type

All Skin Types

Key Ingredients

Peptides from human stem cells
UGL Complex

All Ingredients

Water (Aqua), Caprylic/Capric Triglyceride, Stearic Acid, Butyrospermum Parkii (Shea) Butter, Peptides from Human Stem Cells, Glycerin, Cetyl Alcohol, Glyceryl Stearate, PEG-100 Stearate, Algae Extract, Argania Spinosa Sprout Cell Extract, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, Saccharomyces Cerevisiae Extract, Collagen Amino Acids, Micrococcus Lysate, Phospholipids, Isomalt, Cetearyl Alcohol, Urea, Glucosamine HCL, Ceteareth-20, Niacinamide, Carbomer, Tocopheryl Acetate, Polyvinyl Alcohol Crosspolymer, Retinyl Palmitate, Sodium PCA, Sodium Starch Octenylsuccinate, Calcium Pantothenate, Disodium EDTA, Maltodextrin, Panthenol, Sodium Ascorbyl Phosphate, Lecithin, Ethyl Ferulate, Polyglyceryl-5, Trioleate, Pyridoxine HCL, Ubiquinone, Sodium Benzoate, Silica, Nylon-12 Fluorescent Brightener 230 Salt, Hexylene Glycol, Disodium Uridine Phosphate, Aminomethyl Propanol, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol, Citric Acid.

Once I find what I am looking for, how do I buy it?

When you find an item or items you wish to purchase:
1. Click on the link that reads “Add To Cart”, next to the item description and price. This will add the item to your shopping cart and this then brings you to the cart page which lists all of the products that you have previously selected.
2. On the cart page, you may change the quantities, and then you’ll need to press the “update quantity” link. Your cart will remain available if you leave the page to add new items and return to cart.
3. The cart page will reload and display the total cost of your order. If it does not, just refresh your browser.
4. Click “Proceed to Checkout”, once you are satisfied with your shopping cart contents.
5. After submitting your order, you will receive an email Order Confirmation. If you have difficulties of any sort just call us at (772) 999-5322.

I want to return my Lifeline® ProPlus+ product, can I return it?

If you have questions or concerns, please email us or call us at (772) 999-5322. We are very committed to your satisfaction. You may return any unopened item within 30 days of purchase for a full refund. If your opened product is defective upon shipping, do not use it and we will replace it with the same item.

We will not charge you any shipping to ship a replacement item. Shipping fees, both to and from you, are nonrefundable, and you will be charged a 10% restocking fee, unless the return was made as a result of our error.

Not happy with results? View our money back guarantee.

Are your products safe for pregnant women to use?

Our products are gentle and effective for all skin types. However, we recommend that any woman who is pregnant or breast-feeding check with her physician before changing her skin care routine.

Our products are not tested on animals.

Can men use these products?

Absolutely and positively yes they can. A man’s facial skin is just as sensitive as a woman’s. Products that claim to be strong enough for a man generally have drying and abrasive ingredients like alcohol, silicone based lubricants, petroleum based skin softeners and harsh preservatives that will dry and irritate the skin. Lifeline® ProPlus+ products are as simple and natural as possible to help fight inflammation and balance the skin.

5 reviews for Lifeline® ProPlus+ Daily Defense Complex

  1. Patricia S

    Love this for the extra antioxidants that the night doesn’t have-makes me feel more protected. I used to use the consumer product which is the regular Lifeline stuff you find on like Amazon and Ebay-not the Proplus, but I for sure find that this is stronger, works better and at least on this website, isn’t any more expensive so how cool is that? Also love the eye serum. Great products,all of them,actually.

  2. Latisha

    I like this product but use it at night, rather than during the day. I like it better than the night serum due to the extra stuff it has in it that I feel are protective. However it is too heavy, even tho it’s just a serum, if you have oily skin; for during the day. So IDK what to rate this;like, it works but just don’t get it if you have super oily skin like me;I’m going to try this aqueous serum and i”ll let you know what I think.

  3. Betsy

    Love this product and was using regular Lifeline day and DO indeed notice this is stronger and more effective;especially for fine lines and sagging at jaw.Amazing product and so is night serum and the eye serum. Only reviewing this one but definitely recommend all of these products. This is the best price I’ve found,too. FYI.

  4. Athena Holt

    This product is so light and non-greasy which is what I”m always afraid of with day serums or whatever. And it does indeed work but I found that it worked much better when I also used the night serum which surpise-didn’t feel greasy either. Yes I have oily skin. And I also did have textue issues and spots and lines which are all nicely going away. A definite 5 star product.

  5. Jim in Vegas

    The closer I get to the 50- the more I worry about aging! – I can feel a difference in my skin! I would recommend this for anyone who wants to de-age.

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